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If I have an OCR response above four degrees, does that mean that my patient has normal ocular function?
Okay, thanks for that question. And what I did not really go into detail of the study that I mentioned (in the webinar), were the cutoff values for normal versus abnormal. The reason I didn't go too much into the detail is that it's a very small study, there are only 14 patients in that study and 12 normal individuals. So yes, they actually came up with a cutoff value of what is normal and what's abnormal. But I'd like to see a bigger study. I'll go ahead and give you the number. But consider the fact that this is a small study. So what they found statistically significant was three degrees. If you have less than three degrees of ocular counter rolling reaction that will be considered abnormal. Now that is for both unilateral and bilateral. They found that the difference between unilateral and bilateral was approaching significance. But the p value was not significant. So it didn't quite make it into clinically significant value. If you take three degrees, if the reaction or the response is less than three degrees, there is an abnormality, whether it's a unilateral or bilateral, at least that study did not reference that yet. So, again, I think we'd like a little bit of a bigger study. By the way, the sensitivity and specificity for three degrees as a threshold for abnormality was 80% and 81%.
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